Traumatic spinal cord injury (tSCI) is a devastating condition that causes sensory and motor dysfunction and permanently impairs normal life. Spasticity is one of the most common complications associated with tSCI that limits independent functional abilities. Spasticity is defined as a velocity-dependent increase in muscle tone, in response to passive movement and it is accompanied by pain and stiffness. Unfortunately, current treatments provide only transient and often incomplete relief of spasticity and individuals often experience long-term adverse effects. Through a collaborative project between three labs, we aim to develop a durable non-invasive electrical stimulation treatment to alleviate spasticity. I participated in preparing the model of spasticity by performing spinal surgeries on the cervical spine of rats. To evaluate spasticity, we studied the loss of Rate-Dependent Depression (RDD) of the H-reflex which is considered the electrophysiological hallmark of spasticity. To do so, I fabricated an electrode nerve cuff that was implanted on the median nerve of the rodent’s forearm to study the H-reflex of the affected muscle in the rat’s forelimb. I then recorded and analyzed the temporal development and change of spasticity. H-reflex results validated the spasticity model by showing RDD reduction in injured rats compared to the uninjured rats. The developed treatment shows promising modulation of the H-reflex and recovery of RDD in injured animals. Additionally, to measure velocity-dependent muscle tone, we developed a robotic device that passively moves the rodent’s forearm at different velocities. Employing this robotic behavioral assessment allows me to objectively assess the effect of stimulation on spasticity in the rodent forelimb. Obtained data reveals the muscle resistance to be three times higher in the injured rodent. This novel therapeutic stimulation protocol could potentially be used for clinical use as a non-invasive therapy, to help patients with spasticity in the hand after suffering from cervical tSCI.

As our relationship with public space continues to grow, pedestrianization remains an important tool for reclaiming our space for public social function. Pedestrianization of The Ave is both academically and statistically supported, yet there remains little movement in its favor. Through the lens of placemaking, this project examines the best practices for campaigning the pedestrianization of The Ave in a way that fosters community ownership. Incorporating insight from historical reviews and stakeholder surveys, this research identifies preferred engagement strategies for community stakeholders. Utilizing these findings this research conducts a pilot study and creative visioning that centers community culture. This will result in concepts of a pedestrianization that will best gain public support and feelings of community ownership. These strategies and materials will be compiled as a “campaign” that has the potential to be implemented in the near future. As community planning in the University District seems to be very disconnected from its stakeholders, this project is rooted in community empowerment, seeking to connect people to systems.

The northeastern quadrant of Washington State is an area of vast public lands. It includes 2-3 National Forests, three State Forests, three Indian Reservations, five Wildlife Areas, and 28 Sno-Parks that contain a wide variety of recreational amenities, including kayaking, rafting, horseback riding, snowshoeing, skiing, camping, and backpacking, among others. This area is also part of the Okanogan Dry Forest and Canadian Rockies Mountains ecoregions, which are characterized by dense coniferous forests that are easily ignitable. As a result, the region is regularly impacted by devastating wildfires, which are accompanied by heavy smoke and pose significant threats to local air quality, small town economies, and natural resources. The purpose of this project is to understand how smoke and fire impact two important resources serving tourists in the area: outdoor recreational amenities, and the production of apples and wine. To investigate these impacts, I reviewed data on recent fires that caused damage to orchard and vineyard land, tribal land, recreational land, and private real estate, looking at the cost of this damage in terms of lives and property lost and the particular impacts of smoke hazards. This data was augmented with interviews of local real estate agents, business owners, and members of the Washington State Department of Natural Resources. The final results I'm expecting from this research is on how recreational amenties are impacted by mega-fires that causes devestating damage towards the forest, recreation amenties, local tribes, people lives,property, public health and the community. By doing this reserch it help me get better understanding how we should managed fire on recreational areas in the Okanogan Highlands area by following proper fire suppression tactics and resources. The results of this project help us better understand the growing effects of fire and smoke on this region in general, and on recreational and tourist activity in particular.

As the climate changes, we are beginning to see the impacts on a global scale. In order to understand how our landscapes will change with future warming, we can look back to see how landscapes were impacted by past warm, variable climates. This project looks to understand how climate variability in the Middle Miocene is expressed in terrestrial sedimentary records. Using X-ray fluorescence (XRF) analysis, we created a high-resolution elemental geochemical profile of sediment samples from Clarkia, ID (~16 Ma). From XRF, elemental concentrations for a host of elements, including Ca, Fe, K, Mn, Sr, Ti, Zn, and Zr, were calculated. Some elements, notably Ca, showed long-term trends but also sections of shorter-term cyclic variability. It is possible that this variability reflects changes in basin weathering rates of Ca-bearing minerals as a function of climate change occurring on timescales of tens to hundreds of thousands of years. Alternatively, Ca concentrations may reflect changes to precipitation of Ca-bearing minerals within the ancient lake, responding to algal productivity. These hypotheses are tested using X-ray diffraction (XRD) to identify minerals and their crystalline structures as well as characterizing the elemental trends from an additional site, Clarkia’s P-40. Understanding the depositional history of the Clarkia lakebeds aids our understanding in how climate impacts Miocene landscapes.