Prior to the outbreak of SARS CoV-2, enveloped RNA viruses had been successfully detected in municipal wastewater. Since SARS CoV-2 emergence, researchers have further validated this technique. By March 2020, research suggested viral concentration via wastewater sampling was predictive, by 3-5 days of a subsequent rise in COVID-19 infections. Thus, measuring municipal wastewater quickly became a useful epidemiological tool for COVID-19 management. Despite relative validation, these data provided population level trends, leaving officials little time, or location-specificity, to make use of this warning signal. To address this problem, we partnered with the City of Tacoma Environmental Services Division and Tacoma Pierce County Department of Health (TPCDH) on behalf of RAIN, a Tacoma based biotechnology non-profit, and designed a neighborhood-level rapid response plan. By analyzing health disparities data, wastewater infrastructure and active case rates we sought to illuminate sites of active transmission. To conduct this study, we sampled weekly from two wastewater treatment plants in Tacoma, WA, and five geographically disparate neighborhood sites to monitor SARS CoV-2 levels. We collected population-specific biological samples in each neighborhood for a population-specific SARS-CoV-2 analysis. Using quantitative real-time polymerase chain reaction (qRT-PCR), we successfully isolated SARS-CoV-2 at variable levels in all sample populations between April 2020 and March 2021. Taken together, our data reveal infection trends within a municipal sub-population in absence of individual testing. Additionally, by this method we collect information on the outstanding question of asymptomatic infections. Overall, these data provide health officials geographically specific information to best mobilize limited healthcare resources.