Asthma is a very common chronic childhood illness, affecting approximately 10% of US children. It can lead to significant morbidity and decreased quality of life (QOL) in pediatric patients and their caregivers, on whom the burden of daily asthma management may take a significant toll. However, existing research does not sufficiently describe the relationship between asthma control and parent- and child-reported QOL. The purpose of this study, therefore, is to describe asthma-related QOL in school-aged children and their caregivers and to determine whether asthma control is predictive of QOL. Children aged 6-11 and one caregiver participated in this cross-sectional study. Child-caregiver dyads completed the Childhood Asthma Control Test, Paediatric Asthma Quality of Life Questionnaire, and the Paediatric Asthma Caregiver’s Quality of Life Questionnaire. Descriptive statistics were used to describe the sample demographics and asthma control. Pearson correlations and linear regressions were computed to assess the relationship between asthma control and parent- and child-reported QOL. The study included 33 child-caregiver dyads (child mean age 8.4 years). The children were predominantly male (52.9%), non-Hispanic (73.5%) and white (70.6%). 51.5% had asthma that was not well-controlled. Asthma control is associated with child-reported QOL (r(33)=.49, p=.004) and the parent-reported activity QOL (r(33)=.44, p=.011). While there was not a significant difference in QOL between children with controlled versus uncontrolled asthma, there was a significant difference in parent QOL (t(33)=-2.3, p=.02). A regression analysis found that child asthma control was a significant predictor of child QOL (F(1,31)=9.90, p=.004, R2=.24) but not parent QOL. Parent and child QOL and child asthma control appear to be related, though additional research is needed to clarify this relationship. Our preliminary findings suggest that clinical efforts to improve asthma control might not only decrease risk for asthma-associated morbidity, but also positively impact how patients feel and function in day-to-day activities.