African-born individuals in the United States face unique barriers in accessing preventative healthcare. We conducted a mixed-methods study to implement community-based health fairs and learn in the process the barriers regarding accessing preventative healthcare. From April to May 2018, we held six health fairs at three apartment complexes with high numbers of African-born residents. Fairs included free point-of-care screening for glucose, cholesterol, BMI, blood pressure, and HIV along with social services and health education. The health fairs were hosted in apartment complex common areas with HIV testing conducted in private rooms. Health fair participants were asked to complete a series of questionnaires to evaluate demographics, access to health services, and HIV testing history. We conducted 18 key informant interviews with health fair participants and community leaders to identify barriers to preventative healthcare among African-born individuals. Of the 111 adults who accessed at least one service at a health fair, 92 completed questionnaires. 61% were female, 52% were born in Africa, and 63% had health insurance. Among the 18 interviewed, the most commonly reported barriers were language, logistical barriers, a distrust of health professionals, and lack of health literacy. These barriers create a disconnect between patients and health providers and impedes access to health-related information. A high prevalence of non-communicable diseases was also identified among participants, including obesity, high blood pressure, and high cholesterol. Residential health fairs are a feasible method to increase engagement of African-born individuals in preventative care. Key considerations are providing culturally-competent care, easily accessible services, and staffing services with healthcare providers who speak the primary languages of the populations being served or have adequate interpretation services. Preventative healthcare services will also be more acceptable if all services (e.g. cardiometabolic and HIV screenings) are incorporated into one package and promoted as routine activities.