With the recent legalization of recreational marijuana use in states spanning the country, rates of marijuana use among college students are climbing. Marijuana is one of the most heavily used drugs among young adults and the literature on sex differences in consequences of marijuana use is sparse. This study examined sex differences in marijuana-related negative consequences among college students. Data were collected from students across 9 campuses who indicated past year non-medical use of prescription stimulant medication as part of a larger web-based study. Participants (n=341) reported past year frequency of marijuana use and related consequences using the Rutgers Marijuana Problem Index. Results revealed a main effect of sex on "feeling down about yourself" as a consequence of marijuana use, indicating that men were more likely to endorse this consequence than women. Results also revealed a main effect for marijuana use frequency; indicating heavier users were more likely to report feeling down about themselves, trouble managing their time, and making decisions they later regretted. Two-way interactions between marijuana use frequency and sex were also explored. A marginally significant interaction revealed that male, but not female, frequent users reported feeling down about themselves because of their marijuana use more than less frequent users. We also found a marginally significant interaction among lower frequency users, where men report having trouble managing their time more than women, but this was reversed when looking at higher frequency marijuana users, with women indicating greater endorsement. Lastly, we found that among women, marijuana use frequency was unrelated to making decisions they later regretted. Conversely, among men, more frequent marijuana users reported this consequence more than all other groups, whereas less frequent male marijuana users reported this consequence the least. Differences in consequences associated with marijuana use have implications for intervention efforts for male and female students.