Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder characterized by social and communication deficits as well as restrictive/repetitive behaviors and interests (American Psychiatric Association, 2013). The broader autism phenotype (BAP) is a set of subclinical characteristics that are milder, but qualitatively similar to the defining features of ASDs and are most notably seen in first- and second-degree relatives of individuals with autism (Gerdts, Bernier, Dawson, & Estes, 2013; Ingersoll, Hopwood, Wainer, & Donnellan, 2011). The broader autism phenotype is thought to display the genetic liability to autism, and as BAP characteristics are only part of the total set of autistic deficits, they are thought to represent simpler components that may more easily be tied to underlying genetic causes. While comparisons of BAP traits in parents of simplex (one affected child) and multiplex (multiple affected children) families have potentially suggested different underlying genetic liabilities, there is no research to date comparing these traits in families with identified genetic events. Using the Simon Simplex Collection (SSC), this study looks to explore differences in phenotypic presentation of ASD-related traits by examining the rates of BAP characteristics within simplex families whose autism has been linked to either a de novo (spontaneous) CNV (large structural chromosomal change), a de novo SNV (single base pair change), an inherited event, or has been deemed idiopathic (unknown cause). Parent BAP levels are assessed via two measures, the Broad Autism Phenotype Questionnaire (BAPQ; Hurley, Losh, Parlier, Reznick, & Piven, 2007) and the Social Responsiveness Scale (SRS; Constantino & Gruber, 2005). Mothers and fathers within the four groups are compared on each of the five SRS subscales, the SRS total score, the three BAPQ subscales, and the BAPQ total score. Given the multiple independent and dependent variables, a multivariate analysis of variance (MANOVA) is used to compare scores across groups.