Serpentinization, a geological process that occurs in many settings on Earth, generally involves the reaction of olivine, a mineral component of ultramafic, basaltic rocks, with water. The products of serpentinization reactions, including serpentine, carbonates, talc, and saponite, are mineralogical signatures which indicate geochemical environments and processes that are hospitable to microbial life. On Earth, these processes have been shown to sustain dense microbial communities. The identification of serpentine in particular uniquely indicates that serpentinization reactions have occurred. Therefore, the identification of the mineral serpentine on Mars has significant astrobiological implications. Previous studies have identified serpentine in three geologic settings on Mars using near-infrared spectral data collected by the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) on board the Mars Reconnaissance Orbiter. Minerals are identified by their unique absorptions at specific wavelengths through the examination of CRISM surface reflectance data across 438 wavelengths from 1.0-3.9 microns. Unfortunately, spectral datasets like CRISM contain large volumes of data and each spectrum usually covers an area that contains several unique compositions, or spectral endmembers. Here, we have adapted and applied factor analysis techniques to CRISM data to confirm the previous detections of serpentine and search for new identifications in regions containing olivine-rich basalts. Our methods, factor analysis and target transformation, are more sensitive to subtle, characteristic absorptions as in the spectrum of serpentine than traditional analysis techniques and are a set of methodologies that allow for rapid and automated analysis of large spectral datasets. These methods can be used globally to both identify the number of individual components and test for the presence of and isolate individual endmembers from mixed spectral data. Ultimately, by applying this technique to the global CRISM dataset, we will have a more detailed understanding of aqueous processes like serpentinization on Mars.