Between 2001- 2003 there has been a surge in an ancient yet taboo tradition of bacchabazi in Afghanistan; baccha meaning “child “and bazi meaning “gaming” with a connotative meaning of “boys for play”. This is a significant concern because the act of bacchabazi is one that focuses on the sexual exploitation of young poverty-stricken Afghan boys for the sole purpose of elevating the statuses of their owners, mainly high ranking ex-military officers. By engaging in research of bacchabazi I intend to find answers surrounding why the act of bacchabazi has increased and what the triggers are, that permit it to flourish? The objective of my research is to look at the factors involved in this practice, including aspects of class, socioeconomic status, and conflict areas. The method I am going to use is a feminist discourse analysis of media artifacts current and historical ones. This will include newspapers foreign and domestic, blogs, academic texts, and documentaries reported by researchers within the field of child exploitation in Afghanistan, specifically focused around bacchabazi. This analysis will be done through a lens of transnational feminism while supplementing theories of colonization and post-colonization. Since the theoretical context is colonization and post-colonization, my research will fit into existing related scholarship and contribute to the field because there is not a substantial amount of research currently being published. Since my data is still accumulating I do not have solidified results but rather, informed opinions that would infer recommendations for the young men affected. Some proposed findings/recommendations include: education for the young men with the purpose of identifying the ramifications of being selected/recruited as a bacchabazi, support in way of agency for the young men, and an increased awareness among local jurisdiction in regards to not criminalizing the actions forced upon the young men.

The primate immune system has evolved to counter viral attacks. Yet, after several cross species transmission events of SIV, HIV has infected about 60 million people since the beginning of its epidemic. This is in part due to the ongoing evolutionary arms race between antiviral proteins and viral antagonists. SAMHD1 is an antiviral protein that is degraded by the Vpr protein expressed in HIV and SIV. In this evolutionary arms race, SAMHD1 evolves to escape degradation, while Vpr evolves to bind to these new variants of SAMHD1. African Green Monkeys (AGM) are divided into phenotypically distinct and geographically isolated subspecies, each infected with their own species-specific SIVagm, making them ideal to study. A cloned SAMHD1 gene, Tan4, from AGM has been found to be resistant to Vpr from a number of different viruses, except for one called the tan1 Vpr. Sequencing Tan4 revealed that one residue of its nuclear localization signal was mutated. Since nuclear localization of SAMHD1 is required for degradation by Vpr, we hypothesized Tan4 evolved to be cytoplasmic in order to resist degradation. Using immunoflouresence, our results confirmed Tan4 to be in the cytoplasm. Moreover, we found that tan1 Vpr and Vpr from another AGM subspecies, vervet, share similar gene sequences, but only tan1 can degrade Tan4. Currently, I am constructing chimeras between the two Vpr proteins to find the residues in tan1 responsible for degradation of Tan4. Likewise, two Vpr proteins of the sabeus monkey share similar gene sequences yet cannot degrade the same SAMHD1. My ongoing work explores the mechanisms used by the tan1 and sabeus Vpr proteins to evolve in order to successfully degrade SAMHD1 despite its attempts at escape. This will elucidate a better understanding of the ongoing evolutionary arms race for both primate host and virus survival.

In Washington State, the majority of juvenile offenders are handled by the juvenile criminal justice system. However, juveniles who commit serious violent crimes undergo a process known as declination, in which they are processed as adult defendants in adult courts. These juveniles are typically housed in jail with adult inmates, an experience which nation-wide studies have shown to be severely damaging to both their mental and physical well-being. Research regarding the prevalence of this practice in Washington State is slim. Our report aims to rectify this dearth of information by examining relevant statutes and case law, by interviewing various actors in the criminal justice system—including incarcerated youth themselves—and by sending information requests to all 39 counties in Washington State. The first section of our report will detail the types of declination in Washington and how to distinguish between the four main holding facilities: the Juvenile Detention Center, Juvenile Rehabilitation Administration, jail, and prison. Part two will present statistics regarding the number of declined juveniles held in each county jail since 2009, as well as county policies surrounding these declined individuals. Our preliminary research shows that hundreds of juveniles have been declined and held in jails since 2009. The third section will analyze the repercussions of incarceration on a juvenile’s life, as well as detail our personal interviews with several inmates from the Green Hill Juvenile Rehabilitation Administration. Our final section will analyze the differing opinions on the declination process, as well as present some of our own recommendations for improving the current system. We hope that these ideas will lead to the adoption of policies that will protect both public safety and the well-being of the inmates themselves, and provide these youth with the tools they need to successfully reintegrate into society.

Impulsivity is often found to be related to alcohol use (Pearson and Henson, 2012; Simons, 2003). Additionally, a correlate of alcohol expectancies is increased alcohol use (Hull and Bond, 1986). However, no research to date has looked directly into the association of impulsivity, alcohol expectancies, and alcohol use. Therefore, the present study looks into impulsivity, alcohol use, and alcohol expectancies in high school seniors (N = 3,352, 56.6% Female) from Washington and Sweden. Participants completed a baseline online survey as part of a larger trial that assessed peak blood alcohol content (BAC) in the past 12 months, impulsivity as measured by the sensation seeking scale (Zuckerman, 1964), and alcohol expectancies as measured by the brief Comprehensive Effects of Alcohol questionnaire which consists of positive (sociability, tension-reduction, liquid courage, and sexuality) and negative (cognitive/behavioral impairment, risk/aggression, and self-perception) classifications (CEOA; Fromme, 1993). Regression analyses revealed a significant main effect of impulsivity, cognitive/behavioral impairment, sociability, risk/aggression, and self-perception onto peak BAC (p < .05). However, significant interactions were only found for impulsivity onto risk/aggression and self-perception. A significant moderating effect of risk/aggression onto the relationship between impulsivity and peak BAC (β = .002, F (3, 2913) = 114.71, p < .05) was found such that those with lower impulsivity and lower risk aggression scores (alcohol seen positively) have higher peak BAC. A significant moderating effect of self-perception onto the relationship between impulsivity and peak BAC was also found (β = .001, F (3, 2908) = 132.04, p < .05) suggesting that individuals with lower self-perception scores (alcohol seen positively) and higher impulsivity have higher peak BAC. These results suggest that individuals who are both highly impulsive and have higher positive expectancies for alcohol drink more. Future research should continue to investigate the relationship between alcohol expectancies and impulsivity in vivo.

The low educational attainment of students of Mexican origin in the United States is a growing concern. Research identifies parental involvement (PI) as an important asset to student success and defines it as parents’ active participation in their children’s education at home and at school. Little research addresses the ways Mexican parents help their children during their K-12 education and college-going process, however. To address this gap, this research attempts to understand Mexican parents’ involvement and other factors first year Mexican-American college students perceived as important in shaping their educational success. Semi-structured interviews were conducted with 17-college freshman that identified themselves as Mexican, first-generation, low-income, and migrant/seasonal farmworker background. Based on students’ responses, Mexican parents provide deliberate exposure to agriculture work in order to direct their children towards an educational path. They also provided emotional support and encouragement to their children. Findings indicate that Mexican parents are involved in their children’s education, but in a different form than described by the initial models and definitions of parental involvement. Based on these findings, a new model of parental involvement can be created – one that recognizes Mexican parents’ contributions and guides schools to better work with parents in their efforts to increase the proportion of Mexican origin students going to college.

 In Perlmutter lab’s ongoing study, a combination of activity-based motor training and EMG-triggered electrical spinal stimulation is used as therapeutic intervention for rats with spinal cord injuries (SCI). In addition to the reach training being a form of physical therapy, electromyogram (EMG) electrodes are implemented into rat’s impaired arm and on the spinal cord area that receives related motor commands from the brain. By detecting electrical potentials produced by the skeletal muscle, the electrodes then carry out electrical stimulation on the spinal cord. In response to repetitive and consistent transmission from a presynaptic neuron to a postsynaptic neuron, the connection between two neurons is reinforced as a result of Hebbian “plasticity” or the ability to strengthen or create new synaptic connections with the associated neurons. Although preliminary data suggested greater functional recovery in this novel intervention, many rats did not recover fully. This may be due to discrepancies in the timing between the EMG and the descending command arrival in the spinal cord, preventing optimal timing of the electrical spinal stimulation. In my proposed experiment, I hypothesize that triggering the electrical stimulation from the source of the descending motor commands, the brain, rather than from residual muscle activity will enable better synchronization of the stimulation, hence optimizing the intervention. Instead of EMG electrodes, electrocorticographic (ECoG) electrodes that are designed to detect brain electrical activity will be implanted on the surface of the brain. During the 12-week intervention along with the reaching exercise, a device called the Neurochip will record and trigger the stimulation of spinal cord. The ECoG technique may provide a less noisy signal by recording directly from the brain and enable a better estimate of the occurrence of spinal stimulation, thus maximizing the therapeutic potential of the intervention.